Wissenschaft
Diese Seite zeigt die kompakte Studienübersicht zu objektivierbaren Pathomechanismen bei Long/Post COVID, ME/CFS und Post-Vac. Peer-reviewte Originalstudien, Reviews/Synthesen und Preprints sind optisch klar getrennt.
LONG / POST COVID · 11
Multi-Omics / frühe biologische Risikofaktoren
Multiple early factors anticipate post-acute COVID-19 sequelae.
Peer-reviewed Originalstudie
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Immunprofil / Antikörper / endokrine Signale
Distinguishing features of Long COVID identified through immune profiling.
Peer-reviewed Originalstudie
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Komplement / Thromboinflammation
Persistent complement dysregulation with signs of thromboinflammation in active Long Covid.
Peer-reviewed Originalstudie
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T-Zellen / adaptive Immunität
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2.
Peer-reviewed Originalstudie
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Muskelhistologie / Stoffwechsel / PEM
Muscle abnormalities worsen after post-exertional malaise in long COVID.
Peer-reviewed Originalstudie
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Gewebe-T-Zellaktivierung / virale RNA-Persistenz
Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection.
Peer-reviewed Originalstudie
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Proteomik / lösliche Biomarker / Endotypen
Identification of soluble biomarkers that associate with distinct manifestations of long COVID.
Peer-reviewed Originalstudie
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Single-Cell / Monozyten / Immunfehlregulation
A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID.
Peer-reviewed Originalstudie
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Entzündung / Immunerschöpfung / Stoffwechsel
Long COVID involves activation of proinflammatory and immune exhaustion pathways.
Peer-reviewed Originalstudie
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funktionelle IgG-Effekte / passive Übertragung
Transfer of IgG from long COVID patients induces symptomology in mice.
Peer-reviewed Originalstudie
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Virusreaktivierung / Multi-Omics
Virus reactivation in acute and long COVID-19.
Peer-reviewed Originalstudie
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ME/CFS · 7
Mikrobiom / Metabolom / Krankheitsdauer
Multi-‚omics of gut microbiome-host interactions in short- and long-term ME/CFS patients.
Peer-reviewed Originalstudie
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Single-Cell / Immunzellen / Symptomprovokation
Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation.
Peer-reviewed Originalstudie
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angeborene Immunität / Metabolomik / Belastungsantwort
Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS.
Peer-reviewed Originalstudie
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Energiestoffwechsel / Immunprofil / Gefäße
Mapping the complexity of ME/CFS: Evidence for abnormal energy metabolism, altered immune profile, and vascular dysfunction.
Peer-reviewed Originalstudie
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IgG / Endothel / Mitochondrien / Zytokine
Immunoglobulin G complexes from post-infectious ME/CFS, including post-COVID ME/CFS disrupt cellular energetics and alter inflammatory marker secretion.
Peer-reviewed Originalstudie
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Proteomik / multisystemische Signalwege
Charting the circulating proteome in ME/CFS using cross-system profiling to uncover mechanistic insights.
Peer-reviewed Originalstudie
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Neurostoffwechsel / Hirnstamm / vaskuläre Anpassung
Experimental hypoxia to probe neuro-metabolic and vascular dysregulation in ME/CFS: a multimodal proof-of-concept MRI study.
PREPRINT – nicht peer-reviewed
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POST-VAC · 4
Autoantikörper / periphere Nerven
High serum prevalence of autoreactive IgG antibodies against peripheral nerve structures in patients with neurological post-COVID-19 vaccination syndrome.
Peer-reviewed Originalstudie
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Hautbiopsie / Small-Fiber-Neuropathie
Small fiber neuropathy associated with COVID-19 infection and vaccination: A prospective case–control study.
Peer-reviewed Originalstudie
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immunologische Biomarker / Autoimmunität
Overlapping Clinical Presentation of Long COVID and Postacute COVID-19 Vaccination Syndrome: Phenotypes, Severity, and Biomarkers.
Peer-reviewed Originalstudie
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Small-Fiber-Neuropathie / Immunbalance / T-Zell-Veränderungen
Immune correlates underlying small fiber neuropathy presenting as vaccine-associated post-acute SARS-coronavirus syndrome.
Peer-reviewed mechanistische Originalstudie
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MECHANISTISCHE SYNTHESE
Skelettmuskel / Perfusion / Energiestoffwechsel
Key Pathophysiological Role of Skeletal Muscle Disturbance in Post COVID and ME/CFS: Accumulated Evidence.
Peer-reviewed Review / mechanistische Synthese
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LAUFENDE FORSCHUNG · NOCH NICHT PEER-REVIEWED
Immun- und Antigensignaturen bei Post-Vaccination Syndrome
Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination.
PREPRINT – noch nicht peer-reviewed
Originalpublikation öffnen →
